21-Chloro-9-fluoro-11beta,16alpha,17-trihydroxypregn-4-ene-3,20-dione Cyclic 16,17-Acetal with Acetone
[A topical, synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. Halcinonide exerts its effect by interacting with specific intracellular receptors, and the ligand-receptor complex subsequently modulates gene expressions via the typical glucocorticoid signalling pathway. This results in the synthesis of certain anti-inflammatory proteins as well as in synthesis inhibition of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished. (NCI05) ( NCI )]
UMLS (NCI) C0018513- Steroid
- Pharmacologic Substance
Relation/PAR: Pregnenediones
[DE200] ANTI-INFLAMMATORY, TOPICAL
[DE200] ANTI-INFLAMMATORY, TOPICAL
Relation/CHD: HALCINONIDE 0.025 %
HALCINONIDE 0.1 %
HALCINONIDE 0.1 %
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