[A synthetic derivative of the anthracycline antineoplastic antibiotic doxorubicin. Esorubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. This agent exhibits less cardiotoxicity than the parent antibiotic doxorubicin, but may cause severe myelosuppression. (NCI04) ( NCI )]
UMLS (NCI) C0047760 - Nucleic Acid, Nucleoside, or Nucleotide
- Pharmacologic Substance