A A A+ A- A0 A1 A2 A3 A4 A5 A6 A7 A8 A9 AA AB AC AD AE AF AG AH AI AJ AK AL AM AN AO AP AQ AR AS AT AU AV AW AX AY AZ
ALL1-Related Protein
[Expressed in most adult tissues, including hematopoietic cells, except liver by human MLL2 Gene (TRX Family), alternative 5262-aa (564-Da) and 4957-aa isoforms of Myeloid/Lymphoid or Mixed-Lineage Leukemia Protein 2 are putative nuclear transcription factors of the ASCOM complex likely to play a similar role to ALL1 and TRX, although the target genes have yet to be identified. The 5262-aa isoform contains 5 PHD-type zinc fingers, 1 post-SET domain, 1 RING-type zinc finger, and 1 SET domain; the 4957-aa isoform lacks an N-terminal zinc finger and a PHD finger. MLL2 contains 24 amino acid runs, all but 2 of which are Glu runs; proteins with similar features play roles in transcription, translation, and developmental regulation. ( NCI )]
UMLS (NCI) C1317895ALR
MLL2
Myeloid/Lymphoid or Mixed-Lineage Leukemia Protein 2
MLL2
Myeloid/Lymphoid or Mixed-Lineage Leukemia Protein 2
- Amino Acid, Peptide, or Protein
- Biologically Active Substance
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