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Almotriptan Malate
[The malate salt of almotriptan, a sulfonamide triptan with vasoconstrictor activity. Almotriptan selectively binds to and activates serotonin 5-HT 1B and 1D receptors in the central nervous system (CNS), thereby causing cerebral blood vessel constriction. This may lead to a relief in pain from vascular headaches. Almotriptan may also relieve vascular headaches by preventing the release of vasoactive neuropeptides from perivascular trigeminal axons in the dura mater during a migraine, by reducing extravasation of plasma proteins, and by decreasing the release of other mediators of inflammation from the trigeminal nerve. ( NCI )]
UMLS (NCI) C0937898ALMOTRIPTAN MALATE PREPARATION
- Organic Chemical
- Pharmacologic Substance
Relation/PAR: Almotriptan
Unclassified Ingredients
Unclassified Ingredients
Relation/CHD: ALMOTRIPTAN MALATE 6.25 MG
ALMOTRIPTAN MALATE 12.5 MG
ALMOTRIPTAN MALATE 12.5 MG
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