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Alpha Interferon
[A class of naturally-isolated or recombinant therapeutic peptides used as antiviral and anti-tumor agents. Alpha interferons are cytokines produced by nucleated cells (predominantly natural killer (NK) leukocytes) upon exposure to live or inactivated virus, double-stranded RNA or bacterial products. These agents bind to specific cell-surface receptors, resulting in the transcription and translation of genes containing an interferon-specific response element. The proteins so produced mediate many complex effects, including antiviral effects (viral protein synthesis); antiproliferative effects (cellular growth inhibition and alteration of cellular differentiation); anticancer effects (interference with oncogene expression); and immune-modulating effects (natural killer cell activation, alteration of cell surface antigen expression, and augmentation of lymphocyte and macrophage cytotoxicity). (NCI04) ( NCI )]
UMLS (NCI) C0751598alpha-Interferon
Interferon Alfa
Leukocyte Interferon
Lymphoblast Interferon
Lymphoblastoid Interferon
Recombinant Interferon Alfa
Interferon Alfa
Leukocyte Interferon
Lymphoblast Interferon
Lymphoblastoid Interferon
Recombinant Interferon Alfa
- Amino Acid, Peptide, or Protein
- Pharmacologic Substance
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