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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
B B B0 B1 B4 B7 B8 BA BB BC BD BE BF BG BH BI BK BL BM BN BO BP BR BS BT BU BV BW BX BY BZ
BC BC- BCA BCC BCD BCE BCG BCH BCL BCN BCO BCP BCR BCS BCT BCX

BCL1

[Essential for control of the G1/S transition, cyclin D1 interacts with CDK4 and CDK6 to form a serine/threonine kinase holoenzyme and imparts substrate specificity to the complex. RB regulates cyclin D1 gene expression. Cyclin D1 expression may identify Barrett's esophagus patients at high risk for esophageal carcinoma; risk of progression to adenocarcinoma exhibits an odds ratio of 6.85. The BCL1 and PRAD1 oncogenes involve cyclin D1 gene translocations. (from J Natl Cancer Inst 2000. 92:1282 & 1316, SWISS-PROT P24385, OMIM 168461, and NCI) ( NCI )]
UMLS (NCI) C0174680
 
Amino Acid, Peptide, or Protein
Biologically Active Substance

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