Beta Chemokine Receptor-Like 1
[Up-regulated by chronic inflammation and encoded by human CX3CR1 Gene (CCR Family, Rhodopsin Family), 355-amino acid 40.4-kD high-affinity Fractalkine Receptor is a seven transmembrane protein expressed in brain, peripheral blood leukocytes, and spleen as a regulator of leukocyte endothelial trafficking: chemotaxis, cell migration, and adhesion. CX3CR1 signals through a pertussis toxin sensitive G-protein to induce migration and contains common GPCR features. Tyrosine sulfation enhances fractalkine-induced cell adhesion. Sharing the CX3C motif, RSV G glycoprotein can use CX3CR1 as a receptor. CX3CR1 may be an HIV envelope protein co-receptor with CD4. Homozygous CX3CR1 I249/M280 haplotype enhances infection and progression to AIDS. (from LocusLink, Swiss-Prot, OMIM, and NCI) ( NCI )]
UMLS (NCI) C1143767Chemokine (C-C) Receptor-Like 1
Chemokine (C-X3-C Motif) Receptor 1
Chemokine, CX3C Motif, Receptor 1
CMKBLR1
CMK-BRL-1
CX3C Chemokine Receptor 1
C-X3-C CKR-1
CX3CR1
CX3CR1 Protein
Fractalkine Receptor
Fractalkine Receptor CX3CR1
G Protein-Coupled Receptor 13
G Protein-Coupled Receptor V28
G-Protein Coupled Receptor Family 1
Chemokine (C-X3-C Motif) Receptor 1
Chemokine, CX3C Motif, Receptor 1
CMKBLR1
CMK-BRL-1
CX3C Chemokine Receptor 1
C-X3-C CKR-1
CX3CR1
CX3CR1 Protein
Fractalkine Receptor
Fractalkine Receptor CX3CR1
G Protein-Coupled Receptor 13
G Protein-Coupled Receptor V28
G-Protein Coupled Receptor Family 1
- Amino Acid, Peptide, or Protein
- Receptor
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