[A mixture of the sulfate salts of basic glycopeptide antineoplastic antibiotics isolated from the fungus Streptomyces verticillus. Bleomycin sulfate forms complexes with iron that reduce molecular oxygen to superoxide and hydroxyl radicals which cause single- and double-stranded breaks in DNA; these reactive oxygen species also induce lipid peroxidation, carbohydrate oxidation, and alterations in prostaglandin synthesis and degradation. (NCI04) ( NCI )]
UMLS (NCI) C0005739 - Amino Acid, Peptide, or Protein
- Antibiotic
Relation/PAR: BLEO
Relation/CHD: BLEOMYCIN SULFATE 30 UNT
BLEOMYCIN SULFATE 3 UNT/ML
BLEOMYCIN SULFATE 15 UNT