CD CD1 CD2 CD3 CD4 CD5 CD6 CD7 CD8 CD9 CDA CDB CDC CDD CDE CDG CDH CDI CDK CDL CDM CDN CDO CDP CDR CDS CDT CDV CDW
CD30 Antigen
[Expressed in activated T- and B-cells by human TNFRSF8 Gene (TNFR Superfamily) as distinct serine and tyrosine phosphorylated Long (595-aa, 64-kDa precursor type I membrane protein) and Short (cytoplasmic) isoforms, TNF Receptor 8 contains 6 TNFR-Cys repeats. A positive regulator of apoptosis and receptor for TNFSF8/CD30L, TNFRSF8 interacts with the TRAF1, TRAF2, TRAF3, and TRAF5 mediators of signal transduction and regulates gene expression through NF-Kappa-B activation. A Hodgkin's disease associated antigen, TNFRSF8 limits the proliferative potential of autoreactive CD8 effector T cells and protects against autoimmunity. (NCI) ( NCI )]
UMLS (NCI) C0054950- Amino Acid, Peptide, or Protein
- Immunologic Factor
- Receptor
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