CILASTATIN
[A renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, IMIPENEM, is hydrolyzed by dehydropeptidase-I, which resides in the brush border of the renal tubule, cilastatin is administered with imipenem to increase its effectiveness. The drug also inhibits the metabolism of leukotriene D4 to leukotriene E4. ( MSH )]
UMLS (NCI) C0008777- Lipid
- Pharmacologic Substance
Relation/PAR: Cyclopropanes
Fatty Acids, Monounsaturated
Unclassified Ingredient Preparations
Fatty Acids, Monounsaturated
Unclassified Ingredient Preparations
Relation/CHD: CILASTATIN SODIUM
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