UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
C C- C1 C3 C5 C6 C7 CA CB CC CD CE CF CG CH CI CJ CK CL CM CN CO CP CQ CR CS CT CU CV CW CX CY CZ
CY CY CYA CYB CYC CYE CYF CYK CYL CYM CYP CYS CYT

CYP11B1

[Encoded by human CYP11B1 Gene (Cytochrome P450 Family), 503-aa 58-kDa (precursor) Cytochrome P450 CYP11B1 is a mitochondrial inner membrane P450 heme-thiolate monooxygenase expressed in adrenal cortex with steroid 11-beta-hydroxylase activity and involved in conversion of progesterone to cortisol. The 18 or 19-hydroxylation of steroids and aromatization of androstendione to estrone have also been ascribed to CYP11B1. CYP11B1 defects cause adrenal hyperplasia type IV (AH-IV). CYP11B1/CYP11B2 gene fusion causes glucocorticoid-remediable aldosteronism (GRA). P450 enzymes catalyze reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. (NCI) ( NCI )]
UMLS (NCI) C0038296
 
Amino Acid, Peptide, or Protein
Enzyme
Relation/PAR: Oxygenase

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