Cefepime Hydrochloride
[The hydrochoride salt of a semi-synthetic, beta-lactamase-resistant, fourth-generation cephalosporin antibiotic derived from an Acremonium fungal species with broad-spectrum bactericidal activity. Administered parenterally, cefipime inhibits bacterial cell wall synthesis by binding to and inactivating penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity, resulting in a reduction of bacterial cell wall stability and cell lysis. This agent is more active against a variety of Gram-positive pathogens compared to third-generation cephalosporins. ( NCI )]
UMLS (NCI) C0771284CEFEPIME HYDROCHLORIDE PREPARATION
- Organic Chemical
- Antibiotic
Relation/PAR: Cefepime
Relation/CHD: CEFEPIME HYDROCHLORIDE 1 GM
CEFEPIME HYDROCHLORIDE 2 GM
CEFEPIME HYDROCHLORIDE 500 MG
CEFEPIME HYDROCHLORIDE 2 GM
CEFEPIME HYDROCHLORIDE 500 MG
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