Cefpodoxime
[A third generation semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefpodoxime's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefpodoxime inhibits bacterial septum and cell wall synthesis formation. ( NCI )]
UMLS (NCI) C0055011- Organic Chemical
- Antibiotic
Relation/PAR: [AM103] CEPHALOSPORINS, 3RD GENERATION
Relation/CHD: Cefpodoxime Proxetil
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