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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
C C- C1 C3 C5 C6 C7 CA CB CC CD CE CF CG CH CI CJ CK CL CM CN CO CP CQ CR CS CT CU CV CW CX CY CZ
CY CY CYA CYB CYC CYE CYF CYK CYL CYM CYP CYS CYT

Cyclobutanemethanamine, 1-(4-chlorophenyl)-N,N-dimethyl-alpha-(2-methylpropyl)-, Hydrochloride

[The hydrochloride salt form of sibutramine, a phenethylamine derivative with appetite depressant property. Sibutramine hydrochloride metabolites M1 and M2 competitively inhibit the reuptake of norepinephrine, serotonin, and to a lesser degree dopamine by pre-synaptic nerve terminals, thereby promoting a sense of satiety, leading to a decrease in calorie intake, and possibly an increase in resting metabolic rate. This agent does not exhibit anticholinergic or antihistaminic effects. ( NCI )]
UMLS (NCI) C0142278
 
Organic Chemical
Pharmacologic Substance
Relation/PAR: sibutramine
Relation/CHD: SIBUTRAMINE HYDROCHLORIDE 15 MG
SIBUTRAMINE HYDROCHLORIDE 10 MG
SIBUTRAMINE HYDROCHLORIDE 5 MG

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