D 24851
[A synthetic cytotoxic small molecule that binds to tubulin. Bound to tubulin, D 24851 inhibits tubulin polymerization, cell cycle progression at the G2/M phase and, consequently, tumor cell growth. This agent has been shown to be active against multi-drug resistant tumors. (NCI04) ( NCI )]
UMLS (NCI) C0963638- Organic Chemical
- Pharmacologic Substance
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