FK 506

[complex, lipid-soluble, macrocyclic lactone produced by the Japanese soil bacterium Streptomyces tsukubaensis; experimental immunosuppressant which inhibits T-lymphocyte activation and fungal growth by binding to peptidyl prolyl isomerase, forming a complex which interferes with calcium signaling. ( CSP )]

UMLS (NCI) C0729218

FK506

Organic Chemical
Pharmacologic Substance

Relation/PAR: Antibiotics
[IM600] IMMUNE SUPPRESSANTS

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