[Frizzled 3, encoded by the human FZD3 gene, is a G protein-coupled receptor for Wnt proteins and regulates signal transduction in endothelial cells via beta-catenin. It may function in both normal and pathological vasculature differentiation. It also may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Two isoforms are produced by alternative splicing. This protein is widely expressed with relatively high expression in the CNS, including regions of the limbic system, in kidney, pancreas, skeletal muscle, uterus and testis. (From LocusLink, Swiss-Prot and NCI) ( NCI )]
UMLS (NCI) C1175384Frizzled 3 Protein
Frizzled Homolog 3 (Drosophila)
Frizzled, Drosophila, Homolog of, 3
Fz-3
FZD3
FZD3 Protein
hFz3
- Amino Acid, Peptide, or Protein
- Receptor