Frizzled 7
[Frizzled 7, encoded by the human FZD7 gene, is a G protein-coupled receptor for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression downregulates APC function and enhances beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. (From LocusLink and NCI) ( NCI )]
UMLS (NCI) C1259399Frizzled Homolog 7 (Drosophila)
Frizzled, Drosophila, Homolog of, 7
Frizzled-7
Fz-7
FZD7
FZD7 Protein
FZE3
hFz7
Frizzled, Drosophila, Homolog of, 7
Frizzled-7
Fz-7
FZD7
FZD7 Protein
FZE3
hFz7
- Amino Acid, Peptide, or Protein
- Receptor
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