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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
G G0 G1 G2 G3 G4 GA GB GC GD GE GF GG GH GI GL GM GN GO GP GQ GR GS GT GU GV GW GX GY GZ G%
GA GAB GAC GAD GAG GAI GAL GAM GAN GAP GAR GAS GAT GAU GAV GAY

G Alpha Interacting Protein

[Expressed most in lung, placenta, liver, and heart by human RGS19 Gene (RGS Family), membrane-bound fatty acylated 217-aa 25-kDa Regulator of G-protein Signaling 19 is a guanosine triphosphatase-activating protein, containing 1 RGS domain, that specifically interacts with G protein GAI3 and down-regulates G Alpha i/G Alpha q-linked signaling. Heavily palmitoylated in the Cys string motif and mainly phosphorylated on Ser residues, RGS19 inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, driving them into the inactive GDP-bound form. RGS19 binds to G-Alpha subfamily 1 members and interacts with GIPC PDZ domain. (NCI) ( NCI )]
UMLS (NCI) C0384780
 
Amino Acid, Peptide, or Protein
Biologically Active Substance

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