General Transcription Factor IIA2 12kDa
[Encoded by human GTF2A2 Gene, Transcription Initiation Factor IIA Gamma Chain is the 12-kD gamma subunit of TFIIA, along with 35-kD alpha and 19-kD beta subunits. Accurate transcription initiation on class II genes involves ordered assembly of RNA polymerase II and general initiation factors. The first step involves TATA box recognition by TBP, which may be regulated by TFIIA, a factor that interacts with both TBP and a TAF in TFIID. The TFIIA subunits form a six strand beta-barrel that interacts with TBP and a separate four-helix bundle positioned just upstream of the TBP-TATA complex. (NCI) ( NCI )]
UMLS (NCI) C1336785GTF2A2
TFIIA p12 Subunit
TFIIA-12
TFIIA-Gamma
TFIIAS
Transcription Initiation Factor IIA Gamma Chain
TFIIA p12 Subunit
TFIIA-12
TFIIA-Gamma
TFIIAS
Transcription Initiation Factor IIA Gamma Chain
- Amino Acid, Peptide, or Protein
- Biologically Active Substance
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