General Transcription Factor IIF1 74kDa
[Encoded by human GTF2F1 Gene, 74-kD Transcription Initiation Factor IIF Alpha Subunit is the large subunit of general transcription TFIIF, participating in initiation by RNA polymerase II. TFIIF binds to RNA polymerase II decreasing its affinity for nonspecific DNA and acts at an intermediate stage in initiation complex formation after TFIID associates with DNA, as RNA polymerase II binds to DNA, and before recruitment of TFIIE. GTF2F1 interacts with GTF2F2 to direct transcription initiation and is necessary for transcriptional activation by SRF. (NCI) ( NCI )]
UMLS (NCI) C1336786GTF2F1
TFIIF-Alpha
Transcription Initiation Factor IIF Alpha Subunit
Transcription Initiation Factor RAP74
TFIIF-Alpha
Transcription Initiation Factor IIF Alpha Subunit
Transcription Initiation Factor RAP74
- Amino Acid, Peptide, or Protein
- Biologically Active Substance
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