[The synthetic acetate salt form of hydrocortisone, a corticosteroid with anti-inflammatory and immunosuppressive properties. Hydrocortisone acetate initially binds to the cytoplasmic glucocorticoid receptor; then the receptor-ligand complex is translocated to the nucleus where it initiates the transcription of genes encoding for anti-inflammatory mediators, such as cytokines and lipocortins. Lipocortins inhibit phospholipase A2, thereby blocking the release of arachidonic acid from membrane phospholipids and preventing the synthesis of prostaglandins and leukotrienes. ( NCI )]
UMLS (NCI) C0063077 - Steroid
- Pharmacologic Substance
Relation/PAR: (11beta)-11,17,21-Trihydroxypregn-4-ene-3,20-dione
[OR900] DENTAL AND ORAL AGENTS, TOPICAL OTHER
[OP300] ANTI-INFLAMMATORIES, TOPICAL OPHTHALMIC
Relation/CHD: HYDROCORTISONE ACETATE 0.5 %
HYDROCORTISONE ACETATE 1 %WV
HYDROCORTISONE ACETATE 10 MG
HYDROCORTISONE ACETATE 10 MG/GM
HYDROCORTISONE ACETATE 25 GM
HYDROCORTISONE ACETATE 5 MG
HYDROCORTISONE ACETATE 50 MG/ML
HYDROCORTISONE ACETATE 25 MG
HYDROCORTISONE ACETATE 10 %
HYDROCORTISONE ACETATE 30 MG
HYDROCORTISONE ACETATE 25 MG/ML
HYDROCORTISONE ACETATE 15 MG
HYDROCORTISONE ACETATE 2.5 %
HYDROCORTISONE ACETATE 1 %