UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
I I- I0 I1 I2 I3 I4 I5 I6 I7 I8 I9 IA IB IC ID IE IF IG IH II IK IL IM IN IO IP IQ IR IS IT IU IV IX
IS ISA ISB ISC ISD ISE ISG ISI ISL ISM ISO ISP ISR ISS IST ISU ISW

ISWI Family Protein

[The Drosophila gene Imitation SWI (Iswi) encodes a DNA helicase involved in chromatin modeling. It contains a SNF2 related domain, a MYB DNA binding domain, a DEAD/DEAH box helicase, and a helicase C-terminal domain. Iswi is a component of a 215 kD protein NURF, a nucleosome remodeling complex that facilitates the perturbation of chromatin structure in an ATP-dependent manner. Iswi mediates the hydrolysis of ATP during the remodeling of chromatin. It is also a component of the ATP-utilizing chromatin assembly and remodeling factor ACF and of the chromatin accessibility complex CHRAC. This subunit may serve as the energy-transducing component of chromatin-remodeling machines. Iswi belongs to the SNF2/RAD54 helicase family, SNF2L subfamily. Similar sequences have been identified in Caenorhabditis elegans, Homo sapiens, Mus musculus, Plasmodium falciparum, and Saccharomyces cerevisiae. (from FlyBase 0011604 and NCI) ( NCI )]
UMLS (NCI) C1334143
 
Amino Acid, Peptide, or Protein
Biologically Active Substance

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