[Encoded by human oncogene WHSC1 Gene, 1365-amino acid 152 kD Wolf-Hirschhorn Syndrome Candidate 1 Protein contains a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. WHSC1 is preferentially expressed in rapidly growing embryonic tissues, in a pattern corresponding to affected organs in WHS patients. The nature of the protein motifs and expression pattern suggest that WHSC1 is a good candidate responsible for many of the phenotypic features of WHS; a malformation syndrome associated with hemizygous deletion of the chromosome 4 distal short arm. (OMIM, Swiss-Prot, LocusLink, and NCI) ( NCI )]
UMLS (NCI) C1309784Multiple Myeloma Set Domain Protein
NSD2 Protein
Nuclear Set Domain-Containing 2 Protein
WHSC1
WHSC1 Protein
Wolf-Hirschhorn Syndrome Candidate 1 Protein
- Amino Acid, Peptide, or Protein
- Biologically Active Substance