Ovarian Serous Neoplasm
[Serous tumors make up about one fourth of all ovarian tumors. About 30% to 50% are bilateral. Grossly, the better differentiated tumors consist of cystic masses, usually unilocular, containing a clear but sometimes viscous fluid. Papillary formations are often present. The more malignant tumors tend to be solid and invasive, with areas of necrosis and hemorrhage. It is now accepted that a morphologic spectrum exists in these tumors. At one end is the benign serous cystadenoma and at the other end are serous adenocarcinoma, serous papillary adenocarcinoma and serous papillary cystadenocarcinoma. In between are tumors showing some or all of the features associated with carcinoma but lacking definite stromal invasion. These tumors make up about 15% of all serous tumors and are known as borderline, indeterminate, intermediate, of low malignant potential or possibly malignant. In some serous tumors the fibroblastic stromal component is unduly prominent. Theses tumors can be separated into benign (adenofibroma and cystadenofibroma), borderline and malignant (malignant adenofibroma and malignant cystadenofibroma). —2002 ( NCI )]
UMLS (NCI) C0476122- Neoplastic Process
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