PP2A B Subunit B Prime Alpha

[Ubiquitously expressed (heart and skeletal muscle highest) by human PPP2R5A Gene (PP2A Subunit B Family), serine phosphorylated 486-aa 56-kDa cytoplasmic Protein Phosphatase 2 Regulatory Subunit B Alpha is a subunit of PP2A. A major Ser/Thr phosphatase implicated in negative control of cell growth and division, PP2A core enzyme consists of a 36-kDa catalytic C subunit and a constant 65-kDa regulatory/structural A subunit that interact with either a B regulatory subunit or with cell signaling molecules, that likely modulate substrate selectivity, catalytic activity, and subcellular localization, yielding the trimeric holoenzyme. Combinations of different subunit isoforms can generate many forms of PP2A, which may differ in substrate specificity, subcellular localization, or tissue specific expression. (NCI) ( NCI )]

UMLS (NCI) C1335542

PP2A B Subunit B56 Alpha
PP2A B Subunit PR61 Alpha
PP2A B Subunit R5 Alpha
PPP2R5A
Protein Phosphatase 2 Regulatory Subunit B Alpha
Protein Phosphatase 2A Regulatory Subunit B56 Alpha
Serine/Threonine Protein Phosphatase 2A 56 kDa Regulatory Subunit Alpha

Amino Acid, Peptide, or Protein
Biologically Active Substance

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