[Involved in cell adhesion and signaling, human Integrin-aVBeta3 is composed of type I membrane protein chains Integrin Alpha 5 (disulfide-linked heavy and light chains) and Integrin Beta 3 that recognize RGD sequences. Multiple heterodimeric alpha/beta combinations result in different integrins. aV/beta-3 is a receptor for cytotactin, fibronectin, laminin, MMP-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin, and von Willebrand factor. (NCI) ( NCI )]
UMLS (NCI) C1138427aVBeta3 Integrin
Integrin Alpha-V/Beta-3
Integrin aVBeta3
- Amino Acid, Peptide, or Protein
- Receptor