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coagulation factor XII
[Stable blood coagulation factor activated by contact with the subendothelial surface of an injured vessel. Along with prekallikrein, it serves as the contact factor that initiates the intrinsic pathway of blood coagulation. Kallikrein activates factor XII to XIIa. Deficiency of factor XII, also called the Hageman trait, leads to increased incidence of thromboembolic disease. ( MSH )]
UMLS (CSP) C0015525- Amino Acid, Peptide, or Protein
- Biologically Active Substance
Relation/PAR: Blood Coagulation Factor
Serine Endopeptidases
Serine Endopeptidases
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