[alkaloid ester extracted from the leaves of plants including coca; has powerful central nervous system effects similar to the amphetamines and is a drug of abuse; acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake; it is also a local anesthetic and vasoconstrictor and is clinically used for that purpose. ( CSP )]
UMLS (CSP) C0009170 - Organic Chemical
- Pharmacologic Substance
- Hazardous or Poisonous Substance
Relation/PAR: alkaloid
[CN800] CNS STIMULANTS
local anesthetic
tropane
Dopamine Agonist
[NT300] ANESTHETICS, MUCOSAL
Relation/CHD: crack cocaine
COCAINE HYDROCHLORIDE