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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
E E0 E6 E7 EA EB EC ED EE EF EG EH EI EJ EK EL EM EN EO EP EQ ER ES ET EU EV EW EX EY
ENA ENC END ENE ENG ENH ENI ENK ENL ENM ENN ENO ENP ENR ENT ENU ENV ENZ

Endothelial Plasminogen Activator Inhibitor

[Likely expressed primarily in vascular endothelia by single copy human SERPINE1 Gene (Serpin Family), 402-aa 45-kDa (nonglycosylated, predicted) secreted plasma Plasminogen Activator Inhibitor 1 is an acid-stable glycoprotein in plasma, platelets, and endothelia with structural similarity to angiotensinogen, alpha-1-antitrypsin, and antithrombin III. PAI-1 acts as bait for tissue plasminogen activator, urokinase, and protein C; rapid interaction with TPA may regulate fibrinolysis. SERPINE1 defects cause of PAI-1 deficiency. (NCI) ( NCI )]
UMLS (NCI) C0030190
 
Amino Acid, Peptide, or Protein
Biologically Active Substance

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