[This protein is an epithelial-derived, integral membrane serine protease. It forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis. (from LocusLink) ( NCI )]
UMLS (NCI) C0769218Matriptase
Membrane-Type Serine Protease 1
MT-SP1
Prostamin
Serine Protease TADG-15
ST14
Suppression of Tumorigenicity 14
Suppressor of Tumorigenicity 14
Tumor Associated Differentially Expressed Gene 15 Protein
- Amino Acid, Peptide, or Protein
- Enzyme