[A synthetic agent chemically related to the opiates with anti-diarrheal properties. Loperamide decreases gastro-intestinal motility by effects on the circular and longitudinal muscles of the intestine. Part of its anti-diarrheal effect may be due to a reduction of gastro-intestinal secretion produced by opioid receptor binding in the intestinal mucosa. (NCI04) ( NCI )]
UMLS (NCI) C0023992 - Organic Chemical
- Pharmacologic Substance
Relation/PAR: [GA400] ANTIDIARRHEAL AGENTS
Piperidines
Relation/CHD: LOPERAMIDE HYDROCHLORIDE