[A synthetic HLA-A2-restricted nonapeptide derived from proteinase 3 with potential use in cancer immunotherapy. Cytotoxic T lymphocytes (CTL) primed with proteinase 3 PR1 peptide attack leukemic cells that express proteinase 3 aberrantly. Proteinase 3 is a serine proteinase that activates progelatinase A and is involved in metastasis and angiogenesis. (NCI04) ( NCI )]
UMLS (NCI) C0879440PR1 Leukemia Peptide Vaccine
Proteinase 3:PR1 Peptide
- Amino Acid, Peptide, or Protein
- Pharmacologic Substance
- Immunologic Factor