Lomefloxacin
[A synthetic broad-spectrum fluoroquinolone with antibacterial activity. Lomefloxacin inhibits DNA gyrase, a type II topoisomerase involved in the induction or relaxation of supercoiling during DNA replication. This inhibition leads to a decrease in DNA synthesis during bacterial replication, resulting in cell growth inhibition and eventually cell lysis. ( NCI )]
UMLS (NCI) C0065162- Organic Chemical
- Pharmacologic Substance
Relation/PAR: Quinolones
[AM900] ANTI-INFECTIVES, OTHER
[AM900] ANTI-INFECTIVES, OTHER
Relation/CHD: (+-)-1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, monohydrochloride
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