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UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
M M0 M1 M2 M4 M5 M7 M8 M9 MA MB MC MD ME MF MG MH MI MK ML MM MN MO MP MR MS MT MU MV MY
MI MIA MIC MID MIF MIG MIK MIL MIM MIN MIO MIP MIR MIS MIT MIU MIV MIW MIX MIZ

Minichromosome Maintenance Protein 3

[Minichromosome Maintenance Protein 3, encoded by the MCM3 gene, is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. (From LocusLink) ( NCI )]
UMLS (NCI) C1334766
 
Amino Acid, Peptide, or Protein
Biologically Active Substance

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