P P- P0 P1 P2 P3 P4 P5 P6 P7 P8 P9 PA PB PC PD PE PF PG PH PI PK PL PM PN PO PP PQ PR PS PT PU PV PW PX PY
PENBUTOLOL
[A lipophilic, nonselective beta-adrenergic receptor antagonist with anti-anginal and antihypertensive activities. Penbutolol competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate. This leads to a reduction in cardiac output and lowers blood pressure. In addition, penbutolol prevents the release of renin, a hormone secreted by the kidneys that causes constriction of blood vessels. ( NCI )]
UMLS (NCI) C0030812- Organic Chemical
- Pharmacologic Substance
Relation/PAR: Propanolamines
[CV100] BETA-BLOCKERS/RELATED
[CV100] BETA-BLOCKERS/RELATED
Relation/CHD: PENBUTOLOL SULFATE
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