UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Q Q0 Q1 Q4 Q8 QA QB QC QF QN QO QQ QR QS QT QU QV
QUA QUE QUI

QUINAPRIL

[A prodrug and non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Quinapril is hydrolized into its active form quinaprilat, which binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This abolishes the potent vasoconstrictive actions of angiotensin II and leads to vasodilatation. Quinapril also causes a decrease in angiotensin II-induced aldosterone secretion by the adrenal cortex, thereby promoting diuresis and natriuresis, and increases bradykinin levels. ( NCI )]
UMLS (NCI) C0072857
 
Organic Chemical
Pharmacologic Substance
Relation/PAR: [CV800] ACE INHIBITORS
2 benzazine
Relation/CHD: Quinapril Hydrochloride

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