Ubiquitin Protein Ligase
[Ubiquitin protein ligase enzymes catalyze the formation of a covalent peptide bond between the carboxy-terminal glycine of ubiquitin proteins and lysine alpha-amino group of other proteins. This typically marks proteins for either nonlysosomal proteasomal degradation or targeted transport. Ubiquitination requires sequential action of an activating enzyme, a conjugating enzyme, and a ligase. ( NCI )]
UMLS (NCI) C1256818Ubiquitin Protein Ligase Complex
- Amino Acid, Peptide, or Protein
- Enzyme
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