- 1. E7
- [Complexes with and inactivates Rb protein resulting in disruption of cell cycle regulation. ( NCI )] (UMLS (NCI) C1335333) Papillomavirus Transforming Protein E7;
Viral Protein E7;
=Amino Acid, Peptide, or Protein; Biologically Active Substance | - 3. E7070
- [A drug that belongs to the family of drugs called sulfonamides. It is being studied for its ability to treat cancer. ( NCI )] (UMLS (NCI) C0879271) =Organic Chemical; Pharmacologic Substance ;
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- 2. E7010
- (UMLS (NCI) C0656781) =Organic Chemical; Pharmacologic Substance ;
| - 4. E7389
- [A synthetic analogue of halichondrin B, a substance derived from a marine sponge (Lissodendoryx sp.) with antineoplastic activity. E7389 binds to the vinca domain of tubulin and inhibits the polymerization of tubulin and the assembly of microtubules, resulting in inhibition of mitotic spindle assembly, induction of cell cycle arrest at G2/M phase, and, potentially, tumor regression. (NCI04) ( NCI )] (UMLS (NCI) C1328691) Halichondrin B Analog;
=Organic Chemical; Pharmacologic Substance ;
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