- 1501. Intact
- [Undamaged in any way; whole. ( NCI )] (UMLS (NCI) C0205266) =Qualitative Concept
| - 1551. intercellular cementing substance
- [ ] (UMLS (CSP) C0596786) =Body Substance ;
|
- 1502. Intal
- (UMLS (NCI) C0591652) =Organic Chemical; Pharmacologic Substance
| - 1552. intercellular connection
- [direct contact and connection of a cell with a neighboring cell. ( CSP )] (UMLS (CSP) C0178718) =Body Space or Junction ;
=Cellular Biology;
=synapse;
Communicating Junction;
Occluding Junction;
|
- 1503. INTCRAN VAR V LIG-STRIP
- [ ] (UMLS (ICD9CM) C0176647) =Therapeutic or Preventive Procedure
| - 1553. Intercept
- [ ] (UMLS (CSP) C0598981) =Organic Chemical; Pharmacologic Substance
|
- 1504. Integer Number
- (UMLS (HL7) C1552680) =Quantitative Concept =Quantity;
| - 1554. Intercostal Artery
- (UMLS (NCI) C0459917) =Body Part, Organ, or Organ Component ;
|
- 1505. Integral Membrane Protein
- [A protein that is an integral membrane protein with a transmembrane region. ( NCI )] (UMLS (NCI) C0021699) =Amino Acid, Peptide, or Protein; Receptor ;
| - 1555. intercostal muscle
- [Respiratory muscles that arise from the lower border of one rib and insert into the upper border of the adjoining rib, and contract during inspiration or respiration. (From Stedman, 25th ed) ( MSH )] (UMLS (CSP) C0021724) =Body Part, Organ, or Organ Component
|
- 1506. integrase
- [retrovirus encoded protein which covalently links the viral cDNA to host DNA; forms a 'preintegration complex' and catalyzes the viral integration reaction. ( CSP )] (UMLS (CSP) C0063690) =Amino Acid, Peptide, or Protein; Enzyme ;
=Viral Protein;
| - 1556. Intercostal Nerve
- [The ventral rami of the thoracic nerves from segments T1 through T11. The intercostal nerves supply motor and sensory innervation to the thorax and abdomen. The skin and muscles supplied by a given pair are called, respectively, a dermatome and a myotome. ( MSH )] (UMLS (NCI) C1285089) =Body Part, Organ, or Organ Component
|
- 1507. Integrin Alpha-V
- [Human integrin alpha-V protein (1048 aa, ~116 kD) is encoded by the integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) gene (ITGAV). This type I membrane protein forms a heterodimer with an integrin beta protein (either the beta-1, 3, 5, 6 or 8 polypeptide). The resulting complex binds to the tripeptide R-G-D, an amino acid sequence present in a number of ligands including vitronectin, fibronectin, fibrinogen, and laminin. Ligand binding regulates cell adhesion, growth and migration. ( NCI )] (UMLS (NCI) C0253930) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
| - 1557. Interdigital Nerve Scar
- (UMLS (NCI) C0311337) =Disease or Syndrome
|
- 1508. Integrin Alpha-V Beta-5 Protein
- (UMLS (NCI) C0083026) =Amino Acid, Peptide, or Protein; Immunologic Factor; Receptor
| - 1558. interdisciplinary collaboration
- [working with others as a team involving medical research and/or patient care. ( CSP )] (UMLS (CSP) C0597720) =Health Care Activity ;
=health care service planning;
health science research |
- 1509. Integrin Beta-4
- [Integrins are transmembrane glycoprotein receptors that mediate cell-matrix or cell-cell adhesion, and transduce signals that regulate gene expression and cell growth. They are heterodimeric molecules consisting of noncovalently linked alpha and beta subunits. All integrin subunits display a cytoplasmic domain that interacts with the cytoskeleton, a transmembrane region, and a large extracellular domain that interacts with the extracellular matrix. The ITGB4 extracellular domain shows 35% identify with other integrin beta subunits, but is the most different among this class of molecules. The transmembrane region is poorly conserved, whereas the cytoplasmic domain showed no substantial identity in any region to the cytoplasmic tails of other integrin beta sequences or to other protein sequences. The integrin alpha-6/beta-4, a receptor for the laminins, is likely to play a pivotal role in the biology of invasive carcinoma. (from OMIM) ( NCI )] (UMLS (NCI) C0253906) =Amino Acid, Peptide, or Protein; Immunologic Factor ;
| - 1559. Interdisciplinary Research
- [Studies that bring together multiple scientific disciplines to address specific issues. ( NCI )] (UMLS (NCI) C0242479) =Occupational Activity ;
|
- 1510. Integrin Beta-5
- [Human integrin beta-5 protein (799 aa, ~88 kD) is encoded by the integrin, beta 5 gene (ITGB5). This type I membrane protein forms a heterodimer with integrin alpha-V protein. The resulting complex binds to the tripeptide R-G-D, an amino acid sequence present in a number of ligands including vitronectin, fibronectin, fibrinogen, and laminin. Ligand binding regulates cell adhesion, growth and migration. ( NCI )] (UMLS (NCI) C0249042) =Amino Acid, Peptide, or Protein; Receptor ;
| - 1560. interest
- [A state of curiosity or concern about or attention to something; to be of importance or consequence. ( NCI )] (UMLS (CSP) C0543488) =Mental Process ;
|
- 1511. Integrin Binding
- [Integrin Binding involves a biophysical interaction between members of the Integrin family of heterodimeric receptors, that typically mediate cell-to-cell and cell-to-extracellular matrix interactions, and another biological molecule, such as a protein. Such interactions often induce alterations in signal transduction cascades that affect cell function. ( NCI )] (UMLS (NCI) C1149503) =Molecular Function ;
| - 1561. Interest Rate Code
- (UMLS (HL7) C1550363) =Intellectual Product =HL7 Vocabulary Version 2.5;
|
- 1512. Integrin, Alpha 5 (Fibronectin Receptor, Alpha Polypeptide) Gene
- [This gene is involved in receptor signaling and plays a role in cellular adhesion. ( NCI )] (UMLS (NCI) C1416488) ITGA5;
ITGA5 Gene;
=Gene or Genome | - 1562. interference microscopy
- [microscopy utilizing a direct beam of light which splits and recombines as it passes through the specimen, forming a pattern that corresponds to variations in the specimen's thickness and refraction; used to examine transparent objects such as living cells. ( CSP )] (UMLS (CSP) C0026023) =Laboratory Procedure ;
=microscopy;
|
- 1513. Integrin, Alpha L (Antigen CD11A (p180), Lymphocyte Function-Associated Antigen 1; Alpha Polypeptide) Gene
- [This gene plays a role in leukocyte intercellular adhesion. ( NCI )] (UMLS (NCI) C1334144) ITGAL;
ITGAL Gene;
=Gene or Genome ;
| - 1563. interfering virus
- [a virus which prevents replication of another virus; may be due to blocking of virus attachment sites or the presence of defective interfering particles which block the replication of competent ones. ( CSP )] (UMLS (CSP) C0042730) =Natural Phenomenon or Process ;
=virus characteristic;
|
- 1514. Integrin, Alpha M (Complement Component Receptor 3, Alpha; Also Known As CD11b (p170), Macrophage Antigen Alpha Polypeptide) Gene
- [This gene plays a role in extracellular matrix interactions and cellular adhesion. ( NCI )] (UMLS (NCI) C1366562) ITGAM;
ITGAM Gene =Gene or Genome | - 1564. interferometry
- [measurement of distances or movements by means of the phenomena caused by the interference of two rays of light. ( CSP )] (UMLS (CSP) C0021730) =Laboratory Procedure =Optical;
|
- 1515. Integrin, Alpha V (Vitronectin receptor, Alpha Polypeptide, Antigen CD51) Gene
- [This gene plays a role in cell communication and angiogenesis. ( NCI )] (UMLS (NCI) C1416494) ITGAV;
ITGAV Gene;
=Gene or Genome | - 1565. Interferon Alfa
- [A highly purified alpha interferon produced by a human lymphoid cell line. Interferon alpha-n1 consists of multiple alpha interferon subtypes, at least two of which are glycosylated. In contrast, recombinant alpha interferons are individual non-glycosylated proteins produced from individual alpha interferon genes. Alpha interferons bind to specific cell-surface receptors, resulting in the transcription and translation of genes whose proteins have antiviral, antiproliferative, anticancer, and immune-modulating effects. (NCI04) ( NCI )] (UMLS (NCI) C0699817) =Amino Acid, Peptide, or Protein; Pharmacologic Substance
|
- 1516. Integrin, Alpha X (Antigen CD11C (p150), Alpha Polypeptide) Gene
- [This gene is involved in the initiation of immune cell chemotaxis and phagocytosis. ( NCI )] (UMLS (NCI) C1334145) ITGAX;
ITGAX Gene;
=Gene or Genome ;
| - 1566. Interferon Alfa/Isotretinoin/Paclitaxel
- (UMLS (NCI) C0879497) =Therapeutic or Preventive Procedure ;
|
- 1517. Integrin, Beta 2 (Antigen CD18 (p95), Lymphocyte Function-Associated Antigen 1; Macrophage Antigen 1 (MAC-1) Beta Subunit) Gene
- [This gene is involved in the mediation of cellular adhesion and cell-surface signal transduction. ( NCI )] (UMLS (NCI) C1334146) ITGB2;
ITGB2 Gene;
=Gene or Genome ;
| - 1567. Interferon Alfa/Lamivudine/Zidovudine
- (UMLS (NCI) C1134708) =Therapeutic or Preventive Procedure ;
|
- 1518. Integrin, Beta 3 (Platelet Glycoprotein IIIa, Antigen CD61) Gene
- [This gene plays a role in the mediation of platelet aggregation and wound repair. ( NCI )] (UMLS (NCI) C1416498) ITGB3;
ITGB3 Gene;
=Gene or Genome | - 1568. Interferon Alfa/Lutetium Lu 177 Monoclonal Antibody CC49/Paclitaxel
- (UMLS (NCI) C0935676) =Therapeutic or Preventive Procedure
|
- 1519. Integrin, Beta 4 Gene
- [This gene plays a role in cellular adhesion and extracellular matrix interactions. The gene has also been linked to carcinoma invasiveness through signal transduction pathways. ( NCI )] (UMLS (NCI) C1334147) ITGB4;
ITGB4 Gene;
=Gene or Genome ;
| - 1569. Interferon Alfa/Lutetium Lu 177 Monoclonal Antibody CC49/Topotecan
- (UMLS (NCI) C0935677) =Therapeutic or Preventive Procedure
|
- 1520. Integrin, Beta 5 Gene
- [This gene is involved in cell communication and signal transduction. ( NCI )] (UMLS (NCI) C1416501) ITGB5;
ITGB5 Gene;
=Gene or Genome | - 1570. Interferon Alfa/Lymphokine-Activated Killer Cells
- (UMLS (NCI) C0935848) =Therapeutic or Preventive Procedure
|
- 1521. IntegrityCheckAlgorithm
- (UMLS (HL7) C1553730) =Intellectual Product =CodeSystem;
=secure hash algorithm - 1;
secure hash algorithm - 256 | - 1571. Interferon Alfa/Oblimersen
- (UMLS (NCI) C1327948) =Therapeutic or Preventive Procedure; ;
|
- 1522. INTEGUMENT TISS SYMP NEC
- [ ] (UMLS (ICD9CM) C0159037) =Sign or Symptom
| - 1572. Interferon Alfa/Paclitaxel/Yttrium Y 90 Monoclonal Antibody CC49
- (UMLS (NCI) C0935678) =Therapeutic or Preventive Procedure
|
- 1523. Integumentary System Finding
- (UMLS (NCI) C1291044) =Finding ;
| - 1573. Interferon Alfa/SU5416
- (UMLS (NCI) C0935695) =Therapeutic or Preventive Procedure
|
- 1524. Integumentary System Part
- (UMLS (NCI) C1300680) =Body Part, Organ, or Organ Component
| - 1574. Interferon Alfa/Temozolomide
- (UMLS (NCI) C1134620) =Therapeutic or Preventive Procedure ;
|
- 1525. Integumentary System Signs and Symptoms
- [Patient complaints (symptoms), physical and/or laboratory findings related to the skin or integument. ( NCI )] (UMLS (NCI) C1334192) =Sign or Symptom ;
| - 1575. Interferon Alfa/Thalidomide
- (UMLS (NCI) C0879569) =Therapeutic or Preventive Procedure
|
- 1526. intein
- [self-calatytic protein splicing element; in-frame intervening sequence that disrupts a host gene and its protein product. ( CSP )] (UMLS (CSP) C1171311) =Amino Acid, Peptide, or Protein; Biologically Active Substance =gene product;
| - 1576. Interferon Alpha Receptor
- [Human Interferon Alpha Receptor Complex (Type II Cytokine Family Receptor) is a ubiquitous type I membrane protein heteromeric receptor for type I IFNs, alpha and beta, composed of at least 2 chains, IFNAR1 (alpha chain) and IFNAR2 (beta chain). In mediating innate immune responses to viral infection and specific interferon inhibition of virus replication, binding of alpha and beta IFNs triggers tyrosine phosphorylation of JAKs, TYK2, STAT proteins, autophosphorylation, and tyrosine phosphorylation by TYK2. (NCI) ( NCI )] (UMLS (NCI) C0248648) =Amino Acid, Peptide, or Protein; Receptor ;
|
- 1527. intelligence
- [having the capacity to acquire thought and reason and apply knowledge. ( CSP )] (UMLS (CSP) C0021704) =Mental Process =Performance;
| - 1577. interferon beta 1b
- [ ] (UMLS (CSP) C0244713) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor =[IM700] IMMUNE STIMULANTS;
Beta Interferon =Beta-ser-interferon |
- 1528. intended
- [The particpant intends to provide a signature. ( HL7V3.0 )] (UMLS (HL7) C1551357) =Idea or Concept =ParticipationSignature;
| - 1578. Interferon Beta-1A
- [A synthetic version of naturally occuring interferons that have immunomodulatory, antiviral and antiproliferative activities. It may exert antitumor activity by anti-angiogenic and cell differentiation activities. (NCI) ( NCI )] (UMLS (NCI) C0982234) INTERFERON BETA-1A,RECOMBINANT;
INTERFERON BETA-1A,RECOMBINANT PREPARATION;
Recombinant interferon beta-1a =Amino Acid, Peptide, or Protein; Pharmacologic Substance =interferon beta 1a;
=INTERFERON BETA-1A,RECOMBINANT 22 MCG/0.5ML;
INTERFERON BETA-1A,RECOMBINANT 30 MCG/0.5ML;
INTERFERON BETA-1A,RECOMBINANT 44 MCG/0.5ML;
INTERFERON BETA-1A,RECOMBINANT 30 MCG;
|
- 1529. Intense
- [The degree or magnitude of strength, energy, or feeling. ( NCI )] (UMLS (NCI) C0522510) =Qualitative Concept
| - 1579. Interferon Gamma/Voriconazole
- (UMLS (NCI) C1327961) =Therapeutic or Preventive Procedure; ;
|
- 1530. Intensive care
- [advanced and highly specialized care provided to medical or surgical patients whose conditions are life-threatening and require comprehensive care and constant monitoring; it is usually administered in specially equipped units of a hospital. ( CSP )] (UMLS (HL7) C0085559) =Health Care Activity ;
=hospital;
hospital patient care;
Level of Care;
=Coronary care unit;
neonatal intensive care;
◊ (UMLS (HL7) C1548354) Biomedical Occupation or Discipline Specialty Type; | - 1580. interferon inducer
- [agents that promote the production and release of interferons; they include mitogens, lipopolysaccharides, and the synthetic polymers Poly A-U and Poly I-C; viruses, bacteria, and protozoa have been also known to induce interferons. ( CSP )] (UMLS (CSP) C0021742) =Pharmacologic Substance; Immunologic Factor ;
=[AM800] ANTIVIRALS;
biological response modifier;
immunomodulator;
=5'-Inosinic Acid, Homopolymer Complex with 5'-Cytidylic Acid Homopolymer;
|
- 1531. Intensive care unit
- (UMLS (HL7) C1549475) =Idea or Concept =Room type;
| - 1581. interferon receptor
- [Specific molecular sites or structures on or in cells with which interferons react or to which they bind in order to modify the function of the cells. Interferons exert their pleiotropic effects through two different receptors. alpha- and beta-interferon crossreact with common receptors, while gamma-interferon initiates its biological effects through its own specific receptor system. ( MSH )] (UMLS (CSP) C0063699) =Amino Acid, Peptide, or Protein; Immunologic Factor; Receptor
|
- 1532. Intensive care unit
- (UMLS (HL7) C1610734) =Intellectual Product ;
=Hospital unit;
=Pediatric intensive care unit;
| - 1582. interferon registry
- [ ] (UMLS (CSP) C1331080) =Health Care Related Organization
|
- 1533. intent
- [An intention or plan to perform a service.Historical note: in previous RIM versions, the intent mood was captured as a separate class hierarchy, called Service_intent_or_order. ( HL7V3.0 )] (UMLS (HL7) C1550453) =Idea or Concept =ActMoodCompletionTrack;
=appointment;
resource slot;
request;
appointment request;
proposal;
promise | - 1583. Interferon Regulatory Factor 1 Gene
- [This gene plays a role in the transcriptional activation of target genes. It is also involved in promoting apoptosis. ( NCI )] (UMLS (NCI) C1366516) IRF1;
IRF1 Gene =Gene or Genome |
- 1534. Intent
- [An anticipated outcome that is the meaning or purpose for actions taken, thus guiding your planned actions. ( NCI )] (UMLS (NCI) C1283828) =Mental Process
| - 1584. Interferon Regulatory Factor 2
- [Encoded by human IRF2 Gene (IRF Family), transcription factor Interferon Regulatory Factor 2 competitively inhibits IRF1-transcriptional activation of interferons alpha and beta, and perhaps other IRF1-activated genes. IRF2 also functions as a transcriptional activator of histone H4. (NCI) ( NCI )] (UMLS (NCI) C1506302) IRF2;
=Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 1535. Intent To Treat
- [Drug use is intended to improve a pre-existing disease or condition. ( NCI )] (UMLS (NCI) C1292734) Treat;
Treatment Intent =Functional Concept ;
| - 1585. Interferon Regulatory Factor 2 Gene
- [This gene is involved in the repression of IRF1-activated transcription. It also plays a role in the transcriptional activation of target genes. ( NCI )] (UMLS (NCI) C1334138) IRF2;
IRF2 Gene;
=Gene or Genome ;
|
- 1536. Inter
- (UMLS (HL7) C1548610) =Temporal Concept =Repeat;
| - 1586. Interferon Regulatory Factor 3
- [IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. (from LocusLink) ( NCI )] (UMLS (NCI) C0384768) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 1537. Interacinar Cell Pancreatic Polypeptide
- [A 36-amino acid pancreatic hormone that is secreted mainly by endocrine cells found at the periphery of the ISLETS OF LANGERHANS and adjacent to cells containing SOMATOSTATIN and GLUCAGON. Pancreatic polypeptide (PP), when administered peripherally, can suppress gastric secretion, gastric emptying, pancreatic enzyme secretion, and appetite. A lack of pancreatic polypeptide (PP) has been associated with OBESITY in rats and mice. ( MSH )] (UMLS (NCI) C0030298) =Amino Acid, Peptide, or Protein; Neuroreactive Substance or Biogenic Amine; Hormone =pancreas hormone;
=amylin | - 1587. Interferon Regulatory Factor 3 Gene
- [This gene plays a role in the transcriptional activation of target genes. ( NCI )] (UMLS (NCI) C1334139) IRF3;
IRF3 Gene;
=Gene or Genome ;
|
- 1538. Interacting Therapy No Longer Active/Planned
- [Concurrent therapy triggering alert is no longer on-going or planned ( HL7V3.0 )] (UMLS (HL7) C1555294) =Intellectual Product =Therapy Appropriate;
| - 1588. Interferon Regulatory Factor 4
- [Interferon regulatory factor 4 is a transcriptional activator that binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter and to the immunoglobulin lambda light chain enhancer, together with PU.1. IRF4 probably plays a role in the ISRE-targeted signal transduction mechanisms of lymphoid cells. Two isoforms are produced by alternative splicing. (from OMIM 601900 and NCI) ( NCI )] (UMLS (NCI) C0299544) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 1539. Interaction
- (UMLS (HL7) C1546938) =Idea or Concept =Event Qualification;
| - 1589. Interferon Regulatory Factor 4 Gene
- [This gene is involved in the regulation of B-cell differentiation and proliferation. It also plays a role in mediating the proliferation of mitogen-stimulated T cells. ( NCI )] (UMLS (NCI) C0812314) IRF4;
IRF4 Gene =Gene or Genome ;
|
- 1540. InteractionDetectedIssueCode
- (UMLS (HL7) C1697994) =Intellectual Product =AppropriatenessDetectedIssueCode;
=Food Interaction Alert;
Therapeutic Product Alert | - 1590. interferon resource
- [ ] (UMLS (CSP) C1328811) =Health Care Related Organization; ;
|
- 1541. Interactive Continuation
- (UMLS (HL7) C1547180) =Idea or Concept =Continuation style code;
| - 1591. Interferon Therapy
- (UMLS (NCI) C0279030) =Therapeutic or Preventive Procedure
|
- 1542. interactive multimedia
- [integration of audiovisual technology with computer simulated human interaction to control activities and monitor user responses to computer generated questions. ( CSP )] (UMLS (CSP) C0596785) =Intellectual Product ;
=computer human interaction;
informatics | - 1592. Interfollicular Pattern
- (UMLS (NCI) C1334198) =Finding; ;
|
- 1543. interactive therapy
- [ ] (UMLS (CSP) C0872348) =Therapeutic or Preventive Procedure ;
| - 1593. intergenerational
- [ ] (UMLS (CSP) C0598500) =Temporal Concept ;
|
- 1544. InterameningealRoute
- [Interameningeal ( HL7V3.0 )] (UMLS (HL7) C1700023) =Functional Concept =RouteBySite;
=Injection, interameningeal;
| - 1594. interhemispheric transfer
- [transfer of information between cerebral hemispheres. ( CSP )] (UMLS (CSP) C0596787) =Mental Process ;
=brain interhemispheric activity;
|
- 1545. Interaretynoid Leukoplakia
- (UMLS (NCI) C0426552) =Neoplastic Process
| - 1595. InteriorSalish
- (UMLS (HL7) C1698103) =Language =Salishan;
=Okanagan;
Flathead-Kalispel;
Coeur D'alene;
Columbian |
- 1546. INTERAT VEN RETRN TRANSP
- (UMLS (ICD9CM) C0392829) =Therapeutic or Preventive Procedure ;
| - 1596. Interleukin
- [(in-ter-LOO-kins) Biological response modifiers (substances that can improve the body's natural response to infection and disease) that help the immune system fight infection and cancer. These substances are normally produced by the body. They are also made in the laboratory for use in treating cancer and other diseases. ( NCI )] (UMLS (NCI) C0021764) =Amino Acid, Peptide, or Protein; Immunologic Factor
|
- 1547. Interatrial Septum
- [The thin membrane-like muscular structure separating the right and the left upper chambers (HEART ATRIA) of a heart. ( MSH )] (UMLS (NCI) C0225836) =Body Part, Organ, or Organ Component
| - 1597. Interleukin 1 Signal Transducer
- [Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas, human TRAF6 Gene (TRAF Family) encodes 522-aa 60-kDa oligomeric adapter protein and signal transducer TNF Receptor-Associated Factor 6, containing a MATH domain, a RING-type zinc finger, 2 TRAF-type zinc fingers, and a coiled coil domain that mediates homo- and hetero-oligomerization. The MATH/TRAF domain binds to receptor cytoplasmic domains. In mediating TNFR and Toll/IL-1 family signal transduction to diverse pathways, TRAF6 interacts with TNFRSF5, -11A, -11B, -16 and -17, SRC, PKC zeta, IRAK1, -2, and -3, RIPK2, MAP3K1, -5, and -14, CSK, TRIP, TRAF, TTRAP, PELI1, PELI2, and PELI3. TRAF6 activates IKK in the NF-kappa B pathway in response to proinflammatory cytokines and is involved in the IL-1 signaling pathway via MYD88 and IRAK kinases. (NCI) ( NCI )] (UMLS (NCI) C0530129) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 1548. intercalated disc
- [ ] (UMLS (CSP) C0684215) =Cell Component ;
| - 1598. Interleukin 12 Receptor
- [Human high affinity Interleukin 12 Receptor is composed of Interleukin 12 Receptor Beta 1 Chain (I12RB1) and Interleukin 12 Receptor Beta 2 Chain (IL12RB2), each a type I transmembrane disulfide-linked dimer/oligomer protein containing 5 FNIII domains, a box 1 motif required for JAK interaction/activation, and a WSXWS motif for protein folding, intracellular transport, and cell-surface receptor binding. Involved in IL12 signal transduction, IL12RB1 and IL12RB2 oligomers act as low affinity IL12 receptors. (NCI) ( NCI )] (UMLS (NCI) C0255732) =Amino Acid, Peptide, or Protein; Receptor ;
|
- 1549. Intercalated Duct of the Pancreas
- (UMLS (NCI) C0227577) =Body Part, Organ, or Organ Component
| - 1599. Interleukin Gene
- [Interleukin Genes encode Interleukins, soluble cytokine factors produced by leukocytes and other cell types that have broad functional activities, particularly in regulating the inflammatory and immune responses of a variety of cell types. Interleukins enhance cell proliferation and differentiation, DNA synthesis, secretion of other biologically active molecules, and responses to immune and inflammatory stimuli. (NCI) ( NCI )] (UMLS (NCI) C1334205) =Gene or Genome; ;
|
- 1550. Intercalated Neuron
- [generally neurons which are not motor or sensory; may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions. ( CSP )] (UMLS (NCI) C0021792) =Cell ;
=nerve cell;
| - 1600. interleukin receptor
- [Cell surface proteins that bind interleukins and trigger intracellular changes influencing the behavior of cells. ( MSH )] (UMLS (CSP) C0206553) =Amino Acid, Peptide, or Protein; Immunologic Factor; Receptor
|
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