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Acetamide, N-((4-aminophenyl)sulfonyl)-N-(3,4-dimethyl-5-isoxazolyl)-
[An ester of sulfisoxazole, a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with antibacterial property. Sulfisoxazole acetyl competes with PABA for the bacterial enzyme dihydropteroate synthase, thereby preventing the incorporation of PABA into dihydrofolic acid, the immediate precursor of folic acid. This leads to an inhibition of bacterial folic acid synthesis and de novo synthesis of purines and pyrimidines, ultimately resulting in cell growth arrest and cell death. ( NCI )]
UMLS (NCI) C0081437- Organic Chemical
- Pharmacologic Substance
Relation/PAR: 4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide
Relation/CHD: SULFISOXAZOLE ACETYL 600 MG/5ML
SULFISOXAZOLE ACETYL 500 MG/5ML
SULFISOXAZOLE ACETYL 1 GM/5ML
SULFISOXAZOLE ACETYL 500 MG/5ML
SULFISOXAZOLE ACETYL 1 GM/5ML
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