UMLS. CSP-HL7-ICD9CM-NCI-NDFRT-RXNORM
%
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
A A A+ A- A0 A1 A2 A3 A4 A5 A6 A7 A8 A9 AA AB AC AD AE AF AG AH AI AJ AK AL AM AN AO AP AQ AR AS AT AU AV AW AX AY AZ
AL AL- AL7 ALA ALB ALC ALD ALE ALF ALG ALH ALI ALK ALL ALM ALN ALO ALP ALR ALS ALT ALU ALV ALW ALZ

Alpha-Beta-Omega Interferon Receptor-1

[Encoded by human IFNAR1 Gene (Type II Cytokine Receptor Family), 557-aa 64-kDa (precursor) ubiquitous type I membrane protein Interferon Alpha-Beta Receptor Alpha Chain contains 3 fibronectin type III domains and is the alpha subunit of Interferon Alpha Receptor Complex, a heteromeric receptor for type I IFNs, alpha and beta, composed of at least 2 chains, IFNAR1 (alpha chain) and IFNAR2 (beta chain). In mediating innate immune responses to viral infection and specific interferon inhibition of virus replication, binding of alpha and beta IFNs triggers tyrosine phosphorylation of JAKs, TYK2, STAT proteins, autophosphorylation, and tyrosine phosphorylation by TYK2. (NCI) ( NCI )]
UMLS (NCI) C0380190
 
Amino Acid, Peptide, or Protein
Receptor

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