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Antiserum to Endotoxin Core
[A murine monoclonal antibody raised against endotoxins of Escherichia coli J5 strain with potential antibacterial activity. Monoclonal J5 reacts with lipid A, the key endotoxic component of the lipopolysaccharides (LPS), found mostly in gram-negative bacteria. By binding to endotoxins, monoclonal J5 prevents the initiation of a cascade of events in host cells, including the production of proinflammatory cytokines that eventually leads to the sepsis syndrome. ( NCI )]
UMLS (NCI) C1134511Monoclonal J5
- Pharmacologic Substance
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