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Peplomycin Sulfate
[The sulfate salt of the bleomycin analogue peplomycin. Peplomycin forms complexes with iron that reduce molecular oxygen to superoxide and hydroxyl radicals that cause single- and double-stranded breaks in DNA. This agent appears to show greater antitumor activity than bleomycin; its use is limited due to pulmonary toxicity. (NCI04) ( NCI )]
UMLS (NCI) C0135982- Amino Acid, Peptide, or Protein
- Antibiotic
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