[TRAP220 (thyroid hormone receptor-associated protein) is a recently cloned nuclear receptor coactivator, which interacts with several nuclear receptors in a ligand-dependent manner and stimulates transcription by recruiting the TRAP mediator complex to hormone responsive promoter regions. TRAP220 has been shown to interact with thyroid hormone receptors, vitamin D receptors, peroxisome proliferator-activated receptors, retinoic acid receptors and estrogen receptors. Our work supports the assumption that TRAP220 plays an important role in growth and differentiation of central nervous system and may have a function in certain areas of adult brain. (from Eur J Neurosci. 2002;16:671-83) ( NCI )]
UMLS (NCI) C0755397PPAR Binding Protein
PPARBP
PPARG Binding Protein
Thyroid Hormone Receptor-Associated Protein Complex, 220 KDa Subunit
Thyroid Receptor Interacting Protein 2
TRAP220
- Amino Acid, Peptide, or Protein
- Biologically Active Substance