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alpha,alpha,alpha,alpha',alpha',alpha'-Hexafluoro-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxy-2',5'-xylidide
[A synthetic 4-azasteroid compound. Dutasteride competitively and specifically binds to isoenzymes 1 and 2 of 5 alpha-reductase, forming stable enzyme complexes and inhibiting the conversion of testosterone to 5 alpha-dihydrotestosterone (DHT); the reduction in DHT activity may mitigate or prevent enlargement of the prostate gland. The type 2 5 alpha-reductase isoenzyme is primarily active in the reproductive tissues, while the type 1 isoenzyme is also active in skin and the liver. ( NCI )]
UMLS (NCI) C0754659Avolve,(5alpha,17beta)-N-(2,5-Bis(trifluoromethyl)phenyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide
DUTASTERIDE
DUTASTERIDE UNIDENTIFIED
DUTASTERIDE PREPARATION
DUTASTERIDE UNIDENTIFIED
DUTASTERIDE
DUTASTERIDE UNIDENTIFIED
DUTASTERIDE PREPARATION
DUTASTERIDE UNIDENTIFIED
- Organic Chemical
- Pharmacologic Substance
Relation/PAR: [HS900] HORMONES/SYNTHETICS/MODIFIERS, OTHER
Unclassified Ingredients
Unclassified Ingredients
Relation/CHD: DUTASTERIDE 0.5 MG
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