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positional cloning
[indirect exploration of a genetic disease by learning the location of the responsible gene, isolating and cloning its DNA, and translating the DNA to determine the protein product; by comparing this product with the product of the normal allele, one can also analyze the nature of the normal protein altered by the mutation; called also reverse genetics; do not confuse this term with EXPRESSION CLONING or MOLECULAR CLONING. ( CSP )]
UMLS (CSP) C1656250- Research Activity
Relation/PAR: genetic technique
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