- 1. TP40
- [A chimeric fusion protein containing human transforming growth factor alpha (TGF-a) covalently linked to a truncated form of the bacterial toxin Pseudomonas exotoxin A, PE40, with potential antitumor activity. PE40 lacks the cell-binding domain, but retains domains II and III that are involved in membrane translocation and inhibition of protein synthesis in eukaryotic cells. TGF-a moiety of the TP40 immunotoxin binds to and activates epidermal growth factor receptor (EGFR), a tyrosine kinase receptor overexpressed on certain cancer cells. After internalization, the endotoxin moiety of the immunotoxin-receptor complex causes protein synthesis inhibition via modifying translation elongation factor 2 (EF-2), thereby impedes tumor cell growth and proliferation. ( NCI )] (UMLS (NCI) C0247342) =Amino Acid, Peptide, or Protein; Pharmacologic Substance; Immunologic Factor
| - 4. TPD52
- [This gene plays a role in morphogenesis. It is putatively involved in calcium-mediated signal transduction and regulation of cell proliferation. ( NCI )] (UMLS (NCI) C1336662) TPD52 Gene;
Tumor Protein D52 Gene =Gene or Genome ;
|
- 2. TP53BP2
- [This gene plays an inhibitory role in G2/M cell cycle progression and stimulates the transactivation of pro-apoptotic genes. ( NCI )] (UMLS (NCI) C0812245) TP53BP2 Gene;
Tumor Protein P53 Binding Protein, 2 Gene =Gene or Genome | - 5. TPD52L1
- [This gene is involved in the regulation of cell division. ( NCI )] (UMLS (NCI) C1336661) TPD52L1 Gene;
Tumor Protein D52-Like 1Gene =Gene or Genome ;
|
- 3. TP73
- [This gene is involved in the apoptotic pathway and can have anti or pro apoptotic effects. ( NCI )] (UMLS (NCI) C0812244) TP73 Gene;
Tumor Protein p73 Gene =Gene or Genome | - 6. TPI test
- [Syphilis serodiagnosis employing as the antigen Treponema pallidum obtained from rabbit syphilis orchitis. Treponemes are kept alive for a few hours in a special medium. When syphilitic serum and complement are added and incubated, the treponemes are immobilized, i.e., stop moving. ( MSH )] (UMLS (CSP) C0040839) =Laboratory Procedure ;
|
home
