- 5201. Pulmonary heart disease
- [heart disease due to pulmonary hypertension secondary to disease of the lungs, or its blood vessels, with hypertrophy of the right ventricle.(CSP)] (UMLS (ICPC) C0034072) (Pulmonary heart disease; BIHOTZ BIRIKAZKO KRONIKOA; Pulmonal hjertesygdom; Cor pulmonale; KEUHKOPERAINEN SYDANTAUTI; Coeur pulmonaire chronique; Cor pulmonale/Rechtsherzbelastung; maxalat lev reatit; cor pulmonale; Cuore polmonare cronico; PULMONAL HJERTESYKDOM; Doenca pulmonar cardiaca; Enfermedad pulmonar cardiaca; COR PULMONALE/HOGERKAMMARSVIKT) =Disease or Syndrome =CARDIAC DISORDERS; CIRCULATORY; Diagnosis/Diseases Component; pulmonary circulation obstruction =Hypertension, Pulmonary;
| - 5251. PUR Alpha
- [This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of the gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. (from LocusLink) ( NCI )] (UMLS (NCI) C0291181) =Amino Acid, Peptide, or Protein; Biologically Active Substance ;
|
- 5202. pulmonary immaturity of newborn
- [ ] (UMLS (CSP) C0599328) =Disease or Syndrome ;
| - 5252. PURA
- [This gene plays a regulatory role in DNA replication and transcription. ( NCI )] (UMLS (NCI) C1335290) PURA Gene;
Purine-Rich Element Binding Protein A Gene =Gene or Genome ;
|
- 5203. Pulmonary Pathology
- [The branch of pathology that focuses the causes and nature and effects of diseases of the lungs and respiratory structures. ( NCI )] (UMLS (NCI) C0748168) =Disease or Syndrome
| - 5253. Purdue Pegboard Test
- [The Purdue Pegboard test measures finger dexterity and hand-eye coordination by testing an individual's ability to move hands, fingers, and arms (gross motor movement) and to control movements of small objects (fingertip dexterity). Measurements of the right hand, left hand, and both hands are part of the test. ( NCI )] (UMLS (NCI) C0204462) =Diagnostic Procedure
|
- 5204. Pulmonary Precancerous Condition
- (UMLS (NCI) C1335573) =Disease or Syndrome ;
| - 5254. Pure Erythroid Leukemia in Remission
- [Pure erythroid leukemia that is responding to therapy, i.e. It is not progressing and possibly regressing. ( NCI )] (UMLS (NCI) C1335577) =Neoplastic Process ;
|
- 5205. Pulmonary Rehabilitation
- [The respiratory therapist can assist the chronic pulmonary patient in returning to an optimal role in society by providing an effective program. It includes bronchopulmonary drainage, exercise therapy, and patient education. ( HL7V3.0 )] (UMLS (HL7) C1552326) =Professional or Occupational Group =Respiratory Therapist, Certified;
◊ [The respiratory therapist can assist the chronic pulmonary patient in returning to an optimal role in society by providing an effective program. It includes bronchopulmonary drainage, exercise therapy, and patient education. ( HL7V3.0 )] (UMLS (HL7) C1552340) Professional or Occupational Group Respiratory Therapist, Registered; | - 5255. PURE HYPERCHOLESTEROLEM
- (UMLS (ICD9CM) C0678189) =Disease or Syndrome ;
|
- 5206. pulmonary respiration
- [total exchange of air between the lungs and the outside air, usually measured in liters per minute. ( CSP )] (UMLS (CSP) C0035213) =Laboratory or Test Result; Organ or Tissue Function =lung function;
=apnea;
bronchomotion;
| - 5256. pure line
- [ ] (UMLS (CSP) C0599804) =Organism ;
|
- 5207. Pulmonary Service
- (UMLS (HL7) C1546532) =Health Care Related Organization =Hospital Service;
| - 5257. Pure Red Cell Aplasia
- [Suppression of erythropoiesis with little or no abnormality of leukocyte or platelet production. ( MSH )] (UMLS (NCI) C0034902) =Disease or Syndrome =anemia;
|
- 5208. Pulmonary Sinus
- (UMLS (NCI) C0503361) =Body Part, Organ, or Organ Component
| - 5258. Pure Sideroblastic Anemia
- [A myelodysplastic syndrome characterized by an anemia in which 15% or more of the erythroid precursors are ringed sideroblasts. The ring sideroblast is an erythroid precursor in which one third or more of the nucleus is encircled by granules which are positive for iron stain. It occurs primarily in older individuals. The median survival exceeds 5 years. (WHO, 2001) ( NCI )] (UMLS (NCI) C1264195) RARS;
Refractory Anemia with Ringed Sideroblasts;
=Neoplastic Process |
- 5209. pulmonary stretch receptor
- [stretch receptors found in the bronchi and bronchioles; these are sensors for a reflex which stops inspiration; in humans, the reflex is protective and is probably not activated during normal respiration. ( CSP )] (UMLS (CSP) C0034083) =Body Part, Organ, or Organ Component =stretch receptor;
| - 5259. Purge Status Code
- (UMLS (HL7) C1547622) =Intellectual Product =HL7 Vocabulary Version 2.5;
=The visit is marked for deletion and the user cannot enter new data against it.;
The visit is marked inactive and the user cannot enter new data against it.;
Marked for purge. User is no longer able to update the visit. |
- 5210. Pulmonary Sulcus Neoplasm
- (UMLS (NCI) C1335574) pulmonary sulcus tumor;
=Neoplastic Process ;
| - 5260. Purged
- [A storage status in which a document is no longer available in this system. ( HL7V3.0 )] (UMLS (HL7) C1548399) =Idea or Concept =Document Storage Status;
DocumentStorage |
- 5211. PULMONARY TB NOS-NO EXAM
- [ ] (UMLS (ICD9CM) C0152614) =Disease or Syndrome
| - 5261. Purified Water
- (UMLS (HL7) C0991883) WATER,PURIFIED;
WATER,PURIFIED PREPARATION;
=Pharmacologic Substance; Inorganic Chemical =WATER;
Inactive Ingredient Preparations;
Substance type;
=AQUADERM CREAM;
xylometazoline 1 MG/ML Nasal Solution;
VANICREAM;
Naphazoline 0.5 MG/ML Nasal Solution;
xylometazoline 0.5 MG/ML Nasal Solution;
Diphenhydramine 20 MG/ML / Zinc Oxide 20 MG/ML Topical Lotion;
methylbenzethonium 1 MG/ML Topical Cream;
SALICYLIC ACID 40% OINTMENT(GM);
ALCOHOL 28%/SALICYLIC ACID 0.5% LOTION;
ALCOHOL/GLYCOLIC ACID LOTION;
ALUMINUM ACETATE 1%/CAMPHOR 3%/MENTHOL 0.5%/PHENOL 1% CREAM,TOP;
BENZOIC ACID 12%/SALICYLIC ACID 6% CREAM,TOP;
CARA-KLENZ,SKIN & WOUND CLEANSER;
CARRINGTON INCONTINENCE SKIN KIT;
CHLORHEXIDINE GLUCONATE 0.5%/ISOPROPYL ALCOHOL 70% PAD,TOP;
CLEANSING SHAMPOO;
DIBUCAINE 1% CREAM,TOP;
DIPHENHYDRAMINE 12.5MG/PSEUDOEPHEDRINE 60MG/5ML SYRUP;
HYDROPHILIC OINT,TOP;
MAGNESIUM SALICYLATE 325 MG Oral (systemic) tablet;
MONOBASE CREAM,TOP;
NUSOAP SOAP;
OCUCLENZ OPH,IRRG;
RAYNOX CREAM;
ROSE WATER OINT,TOP;
SKIN CREAM,TOP;
SULFUR 5% SHAMPOO;
SULFUR 5%/SULFURATED POTASH/ZINC OXIDE 10% CREAM,TOP;
UNDECYLENIC ACID 5%/ZINC UNDECYLENATE 20% CREAM,TOP;
VITAMIN E 14% CREAM,TOP;
WATER,PURIFIED 85 % |
- 5212. PULMONARY TULAREMIA
- [ ] (UMLS (ICD9CM) C0339946) =Disease or Syndrome ;
| - 5262. Purimethol
- (UMLS (NCI) C0917847) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
|
- 5213. Pulmonary Valve
- [A valve situated at the entrance to the pulmonary trunk from the right ventricle. ( MSH )] (UMLS (NCI) C0034086) =Body Part, Organ, or Organ Component
| - 5263. purine
- [bicyclic ring structure consisting of fused imidazole and pyrimidine rings, with nitrogen atoms at the 1,3,7, and 9 positions; the basic structure of adenine, guanine, and other biologically important bases. ( CSP )] (UMLS (CSP) C0034140) =Organic Chemical ;
=2-Ring Heterocyclic Compound;
nitrogenous heterocyclic compound =2-Aminopurine;
methylpurine;
oxypurine;
1,7-Dihydro-6H-purine-6-thione;
1H-Purin-6-amine;
1,5-Dihydro-4H-pyrazolo[3,4-d]pryimidin-4-one;
Purinones;
2-Amino 6MP |
- 5214. PULMONARY VALVE DISORDER
- (UMLS (ICD9CM) C0034087) =Disease or Syndrome
| - 5264. purine analog
- [synthetic or natural chemical compounds which resemble naturally occurring purine in structure and/or function. ( CSP )] (UMLS (CSP) C1268902) =Nucleic Acid, Nucleoside, or Nucleotide; Biologically Active Substance ;
=nucleobase analog;
=adenine analog;
azapurine;
guanine analog;
thiopurine;
xanthine analog;
|
- 5215. Pulmonary Valve Replacement
- [Surgery performed with the purpose of replacing a degenerated, calcified, malformed, dysfunctional, etc. pulmonary valve with bioprosthetic, homograft or autograft valve. ( NCI )] (UMLS (NCI) C0190129) =Therapeutic or Preventive Procedure
| - 5265. Purine Antagonist
- [Class of drugs that affect the metabolism and utilization of purines. ( NCI )] (UMLS (NCI) C0280038) =Pharmacologic Substance
|
- 5216. pulmonary valve stenosis
- [narrowing of the opening between the pulmonary artery and the right ventricle. ( CSP )] (UMLS (CSP) C0034089) =Disease or Syndrome; Anatomical Abnormality ;
=Heart Valve Diseases;
=Congenital Infundibular Stenosis;
| - 5266. purine metabolism
- [ ] (UMLS (CSP) C1621315) =Molecular Function
|
- 5217. pulmonary vascular disorder
- [ ] (UMLS (CSP) C0854416) =Disease or Syndrome
| - 5267. Purine Metabolism
- (UMLS (NCI) C0920640) Purine Metabolism Pathway =Functional Concept ;
|
- 5218. pulmonary vein
- [large vein carrying oxygenated blood from lungs to left atrium. ( CSP )] (UMLS (CSP) C0034090) =Body Part, Organ, or Organ Component =vein;
| - 5268. purine metabolism disorder
- [ ] (UMLS (CSP) C0268104) =Disease or Syndrome ;
|
- 5219. PulmonaryRoute
- [Pulmonary ( HL7V3.0 )] (UMLS (HL7) C1700183) =Functional Concept =RouteBySite;
=Inhalation, intermittent positive pressure breathing (ippb);
Inhalation, ventilator;
Inhalation, ventimask;
Instillation, endotracheal tube;
Instillation, nasotracheal tube;
Nebulization, endotracheal tube;
| - 5269. purine nucleoside
- [condensation product of a purine base plus a sugar. ( CSP )] (UMLS (CSP) C0034136) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance ;
=nucleoside;
=inosine;
adenine nucleoside;
guanine nucleoside;
adenosine;
inosine;
|
- 5220. Pulp degeneration
- (UMLS (ICD9CM) C0034100) =Disease or Syndrome
| - 5270. purine nucleotide
- [phosphate ester of a purine nucleoside, particularly the 5' phosphate of a purine in N-glycosidic linkage with ribose or deoxyribose as occurs in nucleic acid. ( CSP )] (UMLS (CSP) C0034137) =Nucleic Acid, Nucleoside, or Nucleotide =nucleotide;
=adenine nucleotide;
guanine nucleotide;
IMP;
adenine nucleotide |
- 5221. Pulp Horn
- [The portion of the pulp chamber that extends towards a cusp. ( NCI )] (UMLS (NCI) C0447400) =Body Space or Junction
| - 5271. purine riboside
- [ ] (UMLS (CSP) C0068476) =Nucleic Acid, Nucleoside, or Nucleotide; Pharmacologic Substance
|
- 5222. pulp obturation
- [ ] (UMLS (CSP) C0599377) =Therapeutic or Preventive Procedure
| - 5272. Purine-Nucleoside Phosphorylase Deficiency
- [PNP reversibly catalyzes the phosphorolysis of the purine nucleosides, (deoxy)inosine and (deoxy)guanosine, to their respective purine bases and the corresponding ribose-1-phosphate. Deficiency in this enzyme is an autosomal recessive cause of combined immunodeficiency. ( NCI )] (UMLS (NCI) C0268125) =Disease or Syndrome ;
|
- 5223. Pulpectomy
- [The complete removal of the dental pulp. ( NCI )] (UMLS (NCI) C0034102) =Therapeutic or Preventive Procedure
| - 5273. purine/pyrimidine metabolism
- [sum of chemical changes that occur within the tissues of an organism consisting of anabolism (biosynthesis) and catabolism of purines or pyrimidines; the buildup and breakdown of purines or pyrimidines for utilization by the organism. ( CSP )] (UMLS (CSP) C0597326) =Molecular Function ;
=Intermediary Metabolism;
|
- 5224. PULPITIS
- [Inflammation of the dental pulp. ( NCI )] (UMLS (ICD9CM) C0034103) =Disease or Syndrome =Dental Pulp Diseases;
| - 5274. purine/pyrimidine metabolism disorder
- [condition in which there is a deviation or interruption in the processing of purine or pyrmidine in the body: its absorption, transport, storage, and utilization. ( CSP )] (UMLS (CSP) C0034139) =Disease or Syndrome =Congenital Metabolic Disorder;
=Gicht;
hypoxanthine guanine phosphoribosyltransferase deficiency;
orotate phosphoribosyltransferase deficiency;
Gicht;
hypoxanthine guanine phosphoribosyltransferase deficiency;
|
- 5225. pulpotomy
- [Surgical amputation of the coronal portion of the dental pulp. ( NCI )] (UMLS (CSP) C0034104) =Therapeutic or Preventive Procedure
| - 5275. Purinergic Receptor
- [any molecular receptor for adenine, guanine, or other purine, or their nucleosides or nucleotides, including cyclic nucleotides other than cAMP (see NT); adenine and ATP are important neurotransmitters, so their receptors are found in neural synapses, among other sites. ( CSP )] (UMLS (NCI) C0034836) =Amino Acid, Peptide, or Protein; Receptor =Cell Surface Receptor;
=cyclic AMP receptor |
- 5226. PULSATING EXOPHTHALMOS
- [ ] (UMLS (ICD9CM) C0155271) =Disease or Syndrome ;
| - 5276. PURPLE
- [Any of a group of colors with a hue between that of violet and red. ( NCI )] (UMLS (NCI) C0439542) =Qualitative Concept
|
- 5227. PULSE
- [The rate of the pulse as observed in an artery, expressed as beats per minute. It can be measured at several anatomical sites, including the wrist, neck, temple, groin, behind the knees, or on top of the foot. (NCI) ( NCI )] (UMLS (NCI) C0232117) =Clinical Attribute
| - 5277. Purpose
- [What something is used for; reason or intention. ( NCI )] (UMLS (NCI) C1285529) =Functional Concept
|
- 5228. Pulse
- [The rhythmic wave within the arteries occurring with each contraction of the left ventricle. ( NCI )] (UMLS (NCI) C0391850) =Physiologic Function ;
| - 5278. purpura
- [small hemorrhage in the skin, mucous membrane or serosal surface, or a group of hemorrhagic diseases characterized by purpuric lesions. ( CSP )] (UMLS (CSP) C0034150) =Disease or Syndrome ;
=blood coagulation disorder;
HEMORRHAGIC COND NOS;
Skin Manifestations;
=Purpura, Thrombocytopenic;
Purpura, Hyperglobulinemic;
ALLERGIC PURPURA;
Purpura, Thrombocytopenic |
- 5229. Pulse Oximetry
- [A non-invasive method that provides estimates of arterial oxyhemoglobin saturation by utilizing selected wavelengths of light to determine the saturation of oxyhemoglobin. ( NCI )] (UMLS (NCI) C0034108) =Diagnostic Procedure
| - 5279. Purpura and other hemorrhagic conditions
- [ ] (UMLS (ICD9CM) C0154300) =Disease or Syndrome
|
- 5230. pulse pressure wave
- [the surge of arterial blood felt by the finger or measured and recorded graphically; an indicator of heart rate and systolic force. ( CSP )] (UMLS (CSP) C0597324) =Organ or Tissue Function ;
=vasomotion;
| - 5280. Purpura/coagulation defects/abnormal platelets
- (UMLS (ICPC) C0497166) (Purpura/coagulation defects/abnormal platelets; PURPURA/KOAGULAZIO AKATSA/PLAKETA ANORMALAK; Purpura/koag def/unorm blodplader; Purpura/stollingsst/afw thromb; PURPPURA/ HYYTYMISHAIRIOT/ POIKKEAVAT VERIHIUTALEET; Purpura/defaut coag/plaq anorm; Purpura/Gerinnungs-/Thrombozyt-Stoer; purpura/beayot bikrisha; purpura/alvadasi/verlemezke zavar; Porpora/difetti coag/piastrine an; PURPURA/KOAGUL.DEF/UNORMAL BLODPL; Purpura/defice coagul/plaq anormal; Purpura/coagulopatias/plq an; PURPURA/KOAG DEFEKT/AVVIKANDE TROMBOCYTER) Purpura/coag defects/abn plate =Disease or Syndrome =BLOOD, BLOOD FORMING ORGANS, LYMPHATICS, SPLEEN; Diagnosis/Diseases Component
|
- 5231. Pulsion Diverticulum
- (UMLS (NCI) C0333111) =Anatomical Abnormality ;
| - 5281. pursuit tracking
- [ ] (UMLS (CSP) C0599242) =Physiologic Function ;
|
- 5232. pulvinar thalami
- [large mass of nuclei forming the most caudal portion of the thalamus and overhanging the geniculate bodies and the dorsolateral surface of the midbrain; divided into four parts: the lateral, medial, inferior, and oral pulvinar nuclei. ( CSP )] (UMLS (CSP) C0152347) =Body Part, Organ, or Organ Component =thalamus;
| - 5282. PURULENT ENDOPHTHALM NOS
- [ ] (UMLS (ICD9CM) C0259800) =Disease or Syndrome
|
- 5233. Pump
- [A device that is used to raise, compress, or transfer liquids or gases and is operated by a piston or similar mechanism. ( HL7V3.0 )] (UMLS (HL7) C1556080) =Intellectual Product =AdministrationMedicalDevice;
| - 5283. Pus
- (UMLS (HL7) C0444185) =Substance ;
=SpecimenEntityType;
◊ (UMLS (HL7) C1546758) Intellectual Product Specimen Source Codes; |
- 5234. pump
- (UMLS (NCI) C0182537) =Medical Device ;
| - 5284. Pus
- (UMLS (NCI) C0034161) =Body Substance ;
|
- 5235. pump (molecular)
- [ ] (UMLS (CSP) C0598846) =Amino Acid, Peptide, or Protein; Biologically Active Substance
| - 5285. pus collection
- [ ] (UMLS (CSP) C0598690) =Pathologic Function
|
- 5236. Pump Prime
- (UMLS (HL7) C1548741) =Laboratory Procedure =Specimen Collection Method;
| - 5286. Push Cap
- [A non-threaded cap that forms a tight-fitting closure on a container by pushing the fitted end into the conatiner opening ( HL7V3.0 )] (UMLS (HL7) C1551384) =Manufactured Object =ContainerCap;
|
- 5237. Pump Specimen
- (UMLS (HL7) C1548742) =Laboratory Procedure =Specimen Collection Method;
| - 5287. Pustule
- (UMLS (HL7) C1546759) =Intellectual Product =Specimen Source Codes;
|
- 5238. Punch Biopsy
- [Removal of a disk of skin tissue, for microscopic examination, using a punch. ( NCI )] (UMLS (NCI) C0191321) =Diagnostic Procedure
| - 5288. putamen
- [largest and most lateral of the basal ganglia lying between the lateral medullary lamina of the globus pallidus and the external capsule; it is part of the neostriatum and forms part of the lentiform nucleus along with the globus pallidus; lesions of the putamen produce athetoid movements on the opposite side of the body. ( CSP )] (UMLS (CSP) C0034169) =Body Part, Organ, or Organ Component ;
=lenticular nucleus;
|
- 5239. PUNCTATE KERATITIS
- (UMLS (ICD9CM) C0259799) =Disease or Syndrome
| - 5289. Putchler modified Bennhold stain
- [Stain, Putchler modified Bennhold ( HL7V3.0 )] (UMLS (HL7) C1293956) =Laboratory Procedure =ObservationMethod;
|
- 5240. PUNCTURE OF LUNG
- [ ] (UMLS (ICD9CM) C0176524) =Therapeutic or Preventive Procedure
| - 5290. Putorius furo
- [ ] (UMLS (CSP) C1658569) =Mammal ;
|
- 5241. Puncture of nasal sinus for aspiration or lavage
- [ ] (UMLS (ICD9CM) C0176375) =Therapeutic or Preventive Procedure
| - 5291. putrescine
- [diamine formed by decarboxylation of arginine and ornithine; a precursor of spermidine. ( CSP )] (UMLS (CSP) C0034170) =Organic Chemical; Neuroreactive Substance or Biogenic Amine =Polyamines;
|
- 5242. PUNCTURE OF SPLEEN
- [ ] (UMLS (ICD9CM) C0176710) =Therapeutic or Preventive Procedure
| - 5292. Puumala virus
- [A species of HANTAVIRUS causing nephropathia epidemica, a mild form of HEMORRHAGIC FEVER WITH RENAL SYNDROME. It is found in most of Europe and especially in Finland, along with its carrier rodent, the bank vole (Clethrionomys glareolus). ( MSH )] (UMLS (CSP) C0205790) =Virus ;
|
- 5243. Puncture of vessel
- [ ] (UMLS (ICD9CM) C0176672) =Therapeutic or Preventive Procedure
| - 5293. PUVA
- (UMLS (NCI) C0853073) PUVA Photochemotherapy =Therapeutic or Preventive Procedure
|
- 5244. Puncture Wound
- (UMLS (NCI) C0033119) =Finding ;
| - 5294. Puyallup Tribe of the Puyallup Reservation, Washin
- (UMLS (HL7) C1554445) =Population Group =NativeEntityContiguous;
|
- 5245. punishment
- [The application of an unpleasant stimulus or penalty for the purpose of eliminating or correcting undesirable behavior. ( MSH )] (UMLS (CSP) C0034119) =Idea or Concept
| - 5295. PV701
- [An attenuated, replication-competent, oncolytic strain of Newcastle disease virus. PV701 selectively lyses tumor cells. The selectivity of this agent is related to defects in the interferon-mediated antiviral response found in tumor cells. (NCI04) ( NCI )] (UMLS (NCI) C1327815) =Pharmacologic Substance ;
|
- 5246. pupil
- [opening at the center of the iris of the eye through which light enters. ( CSP )] (UMLS (CSP) C0034121) =Body Part, Organ, or Organ Component =iris;
| - 5296. PVT1
- [This gene plays a role in the activation of transcription. ( NCI )] (UMLS (NCI) C0812285) PVT1 Gene;
PVT1 Oncogene Homolog, MYC Activator (Mouse) Gene;
=Gene or Genome |
- 5247. PUPILLARY ABNORMALITIES
- [ ] (UMLS (ICD9CM) C0154936) =Finding ;
| - 5297. PVT1
- [The PVT1 protein is a product of the PVT1 gene, involved in some human Burkitt lymphomas, and a putative activator of MYC. (from OMIM 165140 and NCI) ( NCI )] (UMLS (NCI) C0919548) PVT1 MYC Activator;
PVT1 Protein;
=Amino Acid, Peptide, or Protein; Biologically Active Substance |
- 5248. pupillary dilator
- [ ] (UMLS (CSP) C0598913) =Pharmacologic Substance ;
| - 5298. PXD 101
- [A novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. PXD101 targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptosis, promoting cellular differentiation, and inhibiting angiogenesis. PDX101 may sensitize drug-resistant tumor cells to other antineoplastic agents, possibly through a mechanism involving the down-regulation of thymidylate synthase. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=454583&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=454583&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C48812" NCI Thesaurus) ( PDQ )] (UMLS (NCI) C1452684) PXD101;
=Organic Chemical ;
|
- 5249. pupillary reflex
- [contraction of the pupil on exposure of the retina to light; or, any reflex involving the change in the size of the pupil occurring in response to various stimuli. ( CSP )] (UMLS (CSP) C0423049) =Clinical Attribute =reflex;
| - 5299. Pyelitis
- [Inflammation of the KIDNEY PELVIS and KIDNEY CALICES where urine is collected before discharge, but does not involve the renal parenchyma (the NEPHRONS) where urine is processed. ( MSH )] (UMLS (NCI) C0034183) =Disease or Syndrome ;
=Kidney Disease;
=pyelonephritis;
|
- 5250. pupillography
- [detection and measurement of the responses of the pupil of the eye. ( CSP )] (UMLS (CSP) C0597325) =Diagnostic Procedure ;
=eye disorder diagnosis;
| - 5300. Pyelitis or pyelonephritis in diseases classified elsewhere
- (UMLS (ICD9CM) C0156256) =Disease or Syndrome ;
|
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