1-Naphthalenemethanamine, a-methyl-N-(3-(3-(trifluoromethyl)phenyl)propyl)-,(aR)-, Hydrochloride
[An oral calcimimetic. Cinacalcet hydrochloride increases the sensitivity of the calcium-sensing receptors on the chief cells in the parathyroid gland to extracellular calcium, thereby reducing parathyroid hormone secretion. A reduction in parathyroid hormone levels inhibits osteoclast activity, favourably impacts bone-specific alkaline phosphatase, bone turnover, and bone fibrosis, and leads to normalization of serum calcium and phosphate levels. Cinacalcet hydrochloride is a treatment option for primary and secondary hyperparathyroidism and parathyroid carcinoma. ( NCI )]
UMLS (NCI) C1260199CINACALCET HCL UNIDENTIFIED
CINACALCET HCL UNIDENTIFIED
CINACALCET HYDROCHLORIDE
CINACALCET HCL UNIDENTIFIED
CINACALCET HYDROCHLORIDE
- Organic Chemical
- Pharmacologic Substance
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